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MIF also has the chance to connect with embryonic stem cells (ESC). Wang et al. (2012) lose mild on this phenomenon by injecting undifferentiated ESC into the spinal wire of wild-variety mice and MIF knockout mice. Hind limb operate was calculated using the Basso Mouse Scale (BMS), which was initially ordinary for both equally teams of mice. It ev

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CD74 is expressed within the area of renal tubular epithelial cells. Also, these cells Convey minimal amounts of MIF that is enhanced following AKI to make sure adequate materials at the positioning of harm (80, 81). A spontaneous pathological renal phenotype is absent MIF knock-out mice, suggesting minimal to no impact on nutritious organs (82). o